Pipeline

NervGen’s lead therapeutic candidate, NVG-291, is a first-and potentially best-in-class neuroreparative peptide targeting the inhibitory mechanisms associated with chondroitin sulfate proteoglycans (CSPGs). NVG-291 is being evaluated in the Phase 1b/2a CONNECT SCI Study, where NVG-291 demonstrated the ability to increase function, independence, and quality of life in individuals with chronic spinal cord injury up to ten years after injury. NervGen is also evaluating a discovery lead, NVG-300, in preclinical models of neurotraumatic and neurologic conditions with significant unmet medical need. 

Note:
– Preclinical development for traumautic brain injury funded and conducted by the U.S. Department of Defense via the Walter Reed Army Institutute of Research (WRAIR).
– Preclinical development for traumatic hearing loss funded and conducted by the U.S. Department of Defense via the 59th Medical Wing. 
– Discovery lead, NVG-300, developed and discovered internally.